West Hempstead (2) vs. Clarke (7): It’s the Rams against the Rams. Explosive West Hempstead (7-1), led by rushers Tayvon Hall and Enrique McFarlane, has a four-game winning streak and topped Clarke (4-4) by 12 in their Week 2 meeting.

Roosevelt (3) vs. Island Trees (6): The Rough Riders (6-2) have a tough road to repeat, but the talent to do so. Johnnie Akins ran for 293 yards and two touchdowns in a 35-14 win over the Bulldogs (4-4) in Week 4.

V.S North (4) vs. Locust Valley (5): The Spartans (4-4) had an up-and-down regular season but can be dangerous if they limit turnovers. Billy Patsos has 16 touchdowns, while the Falcons (5-3) feature running backs Matt Vezza and Louie Jokinsky.